Wolfram Research

Human Disease Network

A network of human diseases linked by known disorder-gene associations

A network of disorders and disease genes linked by known disorder-gene associations, indicating the common genetic origin of many diseases. Genes associated with similar disorders show both higher likelihood of physical interactions between their products and higher expression profiling similarity for their transcripts, supporting the existence of distinct disease-specific functional modules. Vertex annotations contain "DiseaseID", "Name", and "Disorder". An edge property EdgeWeight describes the number of genes shared each other.

(1284 vertices, 1527 edges)

Examples

Basic Examples

Retrieve the graph:

In[1]:=
ResourceData["Human Disease Network"]
Out[1]=

Summary properties:

In[2]:=
ResourceData["Human Disease Network", All]["Summary"]
Out[2]=

Basic Applications

Find the ID, symbol, and associated disorder of the first 10 vertices in the network:

In[3]:=
g = ResourceData["Human Disease Network"];
In[4]:=
info = {"DiseaseID", "Name", "Disorder"};
In[5]:=
Grid[Prepend[
  Table[AnnotationValue[{g, i}, #] & /@ info, {i, VertexList[g][[;; 10]]}], info], Sequence[
 Frame -> All, Background -> {None, {LightGray, {LightYellow}}}, Alignment -> Left, Spacings -> 1.5]]
Out[5]=

Wolfram Research, "Human Disease Network" from the Wolfram Data Repository (2019) 

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